Melanotan is commonly used as a tanning product to darken the skin. It may also be used for other reasons, such as erectile dysfunction. But using melanotan for any purpose may cause serious health problems.
Note: The FDA has not reviewed melanotan for any use. The FDA also does not consider melanotan to be a legal dietary or cosmetic ingredient in the U.S.
How does melanotan work (mechanism of action)?
Melanotan (also known as melanotan II) is a man-made peptide. It stimulates melanocytes, which are the cells in your body that provide pigment (melanin) to your skin. Melanotan may be found in nasal sprays and products that are injected under the skin (subcutaneous), even though it is not considered a legal ingredient in the U.S. It is sometimes referred to online as the “Barbie drug.”
Since melanotan stimulates the creation of pigment in your skin, it has gained popularity as a tanning product. But using melanotan can cause your skin to darken unevenly. It can also cause your existing moles to grow larger and darker and your body to form many new moles. Additionally, there is concern that long-term use of melanotan can increase your risk for skin cancer (melanoma). See Side Effects for more information.
In addition to telling your body to produce more skin pigment, melanotan can also increase sexual arousal in men and women. In men, it can cause an erection. But some men may have painful and prolonged erections (see Side Effects for more information). Before using melanotan, speak with your health care provider about your other options if you have erectile dysfunction or low sex drive.




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